The bottle for Monterey Fruit Tree Spray Plus RTS would not be able to be used once empty. The bottle contains premeasured concentrate specifically for a one time use. We do have other hose end sprayers that would be recommended instead.
The 16oz Monterey Fruit Tree Spray Plus RTS bottle will cover 2.500 sq ft and the 32 oz will cover 5,000 sq ft. The yield will depend on if you are treating for insects or a disease and also the size of the trees, the amount of foliage and the height. Please review the product label here for specific application instructions.